Publications (in reverse chronological order):

  1. Punnoose EA, Ferraldeschi R, Szafer-Glusman E, Tucker EK, Mohan S, Flohr P, Riisnaes R, Miranda S, Figueiredo I, Rodrigues DN, Omlin A, Pezaro C, Zhu J, Amler L, Patel P, Yan Y, Bales N, Werner SL, Louw J, Pandita A, Marrinucci D, Attard G, de Bono J., "PTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients." (2015) Br J Cancer. 113(8): 1225-33. 
  2. Werner SL, Graf RP, Landers M, Valenta DT, Schroeder M, Greene SB, Bales N, Dittamore R, Marrinucci D., "Analytical Validation and Capabilities of the Epic CTC Platform: Enrichment-Free Circulating Tumour Cell Detection and Characterization." (2015) J Circ Biom. 4(3): Epub.
  3. Kearns JD, Bukhalid R, Sevecka M, Tan G, Gerami-Moayed N, Werner SL, Kohli N, Burenkova O, Sloss CM, King AM, Fitzgerald JB, Nielsen UB, Wolf BB. Enhanced Targeting of the EGFR Network with MM-151, an Oligoclonal Anti-EGFR Antibody Therapeutic." (2015) Mol Cancer Ther. 14(7): 1625-36. 

  4. Behar M, Barken D, Werner SL, Hoffmann A. "The dynamics of signaling as a pharmacological target." (2013) Cell. 155(2): 448-61.
  5. Song EJ*, Werner SL*, Neubauer J, Stegmeier F, Aspden J, Rio D, Harper JW, Elledge SJ, Kirschner MW, Rape M. "The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome." (2010) Genes Dev. 24(13): 1434-47. 
  6. Werner SL, Kearns JD, Zadorozhnaya V, Lynch C, O'Dea E, Boldin MP, Ma A, Baltimore D, Hoffmann A. "Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20." (2008) Genes Dev. 22(15): 2093-101.
  7. O'Dea EL, Barken D, Peralta RQ, Tran KT, Werner SL, Kearns JD, Levchenko A, Hoffmann A. "A homeostatic model of IkappaB metabolism to control constitutive NF-kappaB activity." (2007) Mol Syst Biol. 3(111): Epub.
  8. Basak S, Kim H, Kearns JD, Tergaonkar V, O'Dea E, Werner SL, Benedict CA, Ware CF, Ghosh G, Verma IM, Hoffmann A. "A fourth IkappaB protein within the NF-kappaB signaling module." (2007) Cell. 128(2): 369-81.
  9. Kearns JD, Basak S, Werner SL, Huang CS, Hoffmann A. "IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression." (2006) J Cell Biol. 173(5): 659-64. 
  10. Cheong R, Bergmann A, Werner SL, Regal J, Hoffmann A, Levchenko A. "Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses." (2006) J Biol Chem. 281(5): 2945-50.
  11. Werner SL, Barken D, Hoffmann A. "Stimulus specificity of gene expression programs determined by temporal control of IKK activity". (2005) Science. 309(5742): 1857-61.